This document summarizes a study on the seismic analysis and design of symmetric and asymmetric multi-story buildings. Finite element software was used to model and analyze G+15 story reinforced concrete buildings with regular and irregular configurations subjected to response spectrum analysis and time history analysis. Results found that irregular buildings experienced higher displacements, drifts, and forces compared to regular structures. Specifically, structures with mass or stiffness irregularities performed poorer under seismic loads. A comparison of response spectrum and time history analyses found that time history analysis more accurately predicted structural response. The study concluded that structural configuration significantly impacts seismic response and irregular structures are more vulnerable during earthquakes.