This document discusses healthcare-associated infections (HAIs) and presents information from AdvaMed. It notes that HAIs occur worldwide and affect hundreds of millions annually, increasing morbidity, mortality, and costs. Up to 90% of HAI deaths in the US are caused by multi-drug resistant organisms. Surveillance shows HAI incidence is 3 times higher in developing economies compared to EU/US. HAIs lead to prolonged hospital stays and increased costs. Prevention through evidence-based interventions could reduce HAIs by 65-70% and save resources. Strong infection control including surveillance is needed to combat HAIs and antimicrobial resistance.