尊敬的 微信汇率:1円 ≈ 0.046166 元 支付宝汇率:1円 ≈ 0.046257元 [退出登录]
SlideShare a Scribd company logo
Alessandro Pontes-Arruda,LLB, MD, MSc, PhD, FCCM
Overview of emerging infectious disease
issues in the Asia Pacific region
Antimicrobial resistance (AMR) &
Healthcare associated infection (HAI)
Bugs strike back !
Global crisis of AMR
TIME magazine (June 26, 2006)
Molton JS, et al. Clin Infect Dis 2013 doi: 10.1093/cid/cit020.
NDM-1 positive Enterobacteriaceae
Boston
2010
Guatemala
2011
UK
2009
Sweden
2008
Singapore
2011
Japan
2009
Sydney
2010
Kenya
2009
South Africa
2011
India
2008
KPC positive Klebsiella pneumoniae
North
Carolina
1996
UK
2009 Greece
2007
Israel
2004
South Africa
2011
China
2004
Singapore
2010
Sydney
2010
Colombia
2008
Brazil &
Argentina
2008
Global crisis of AMR
AMR is an emerging infectious disease that spreads globally
WHO and WEF highlight the clinical and economic risk* of AMR
Impact of AMR
Antimicrobial resistance ; Global report on surveillance, World Health Organization (WHO), April 2014 ;
World Economic Forum. Global Risks 2013. 8th Ed. & 2014, 9th Ed.
* Losses to GDP : 0.4 ~ 1.6 %
Major examples of AMR
Asia is an epicenter of AMR in most bacterial pathogens
* Highest reported prevalence of resistance to prototype antibiotics, + CAP : community-acquired pneumonia, HAP : Hospital-acquired pneumonia
Community
pathogen
Disease Antibiotic % resistance* Focus area
S. pneumoniae CAP+ Macrolide 73% Asia
E. coli UTI 3rd Cephalosporins 95% Asia
S. typhi Enteric infection Ciprofloxacin 84% Asia
Hospital
pathogen
Disease Antibiotic % resistance* Focus area
S. aureus HAP+, bacteremia Methicillin 82% Asia
E. coli HAP, bacteremia Ciprofloxacin 96% Asia
K. pneumoniae HAP, bacteremia 3rd Cephalosporins 81% Asia
P. aeruginosa HAP Carbapenem 30% Asia
A. baumanii HAP Carbapenem 68% Asia
WHO, Antimicrobial Resistance : Global report on surveillance. 2014; Kim SH, et al. AAC, 2012;56(3):1418-26; Chung DR, et
al. Am J Respir Crit Care Med. 2011;184(12):1409-17; Singhal L, et al. Indian J Med Microbiol. 2014;32(2):149-52
Global strategy to combat AMR
APEC has been focusing on AMR since 2010
“International campaign program
to control AMR in the AP region”2nd project
(2012-2013)
“International initiatives
to control AMR in the AP region”1st project
(2010-2011)
“APEC symposium on control and
prevention of AMR”3rd project
(2013)
“Implementation of international
Campaign program to control AMR”4th project
(2014)
Control of
AMR
Surveillance
of AMR and
antibiotic
use
Infection
control
Increased
awareness
Appropriate
use of
antibiotics
Policy &
regulation
Vaccination
APEC strategy to combat AMR
APEC AMR projects proposed six major action plans
Song JH. APEC project : International initiatives to control AMR. 2011.
Country Program Year of established
14
countries
Asian Network for Surveillance of Resistant Pathogens
(ANSORP)
1996
Korea
 Korean Network for Studies on Infectious Diseases
(KONSID)
 Korean Nationwide Surveillance of Antimicrobial Resistance
(KONSAR)
1997
China
Ministry of Health National Antimicrobial Resistance
Surveillance Net (Mohnarin)
2004
Japan Japanese Nosocomial Infection Surveillance (JANIS) 2000
Malaysia Malaysia Antibiotic Resistant Surveillance Program (MARSP) 1990
Philippines National antimicrobial resistance surveillance program 1988
Singapore The Network for Antimicrobial Resistance Surveillance
Taiwan Taiwan Nosocomial Infections Surveillance System (TNIS) 2007
Thailand
 National Antimicrobial Resistance Surveillance of Thailand
(NARST)
Surveillance of AMR in AP region
There are a few surveillance programs in the region
Song JH. APEC project : International initiatives to control AMR. 2011.
Surveillance of AMR in AP region
ANSORP is the representative international system in Asia
Organizer : Jae-Hoon Song
Headquarter : Samsung Medical Center
Local Network Organizers (LNO)
ANSORP Member Hospitals
Principal & co-investigators
Local ANSORP Networks (LAN) Headquarter
Japan
India
Thailand
Vietnam
Hong Kong
China
Philippines
Taiwan
Malaysia
Singapore
Indonesia
Sri Lanka
Saudi Arabia
Korea
14 countries/area
65 cities,
111 hospitals,
201 investigators
Surveillance of AMR in AP region
There are major hurdles of AMR surveillance in AP region
Lack of awareness
about impact of AMR
Lack of laboratory capacity
and standard platform
Limited funding and
human resources
Lack of national and
regional coordination
No international program
in Asian countries
Awareness of AMR
Antibiotic awareness campaign is urgently needed
Professional society /
Government
Awareness of AMR
Campaign 4 is a new international awareness campaign in Asia
Awareness of AMR
Campaign 4 will be introduced to Asia
Website : www.campaign4.org / www.icareproject.org
Van Boeckel TP, et al. Lancet Infect Dis. 2014. S1473-3099(14)70780-7.
Appropriate use of antibiotics
Asia showed increased antibiotic consumption (2000 to 2010)
• Antibiotics account for 28% of global counterfeit drugs
- Counterfeit antibiotics account for 5% of global antibiotic market
• 78% of them were made in SE Asia
• 44% of them were consumed in SE Asia
Counterfeit
antibiotic
use
South-East
Asia, 44%
Sub-Saharan
Africa, 30%
Europe &
North America,
9%
Others, 17%
No active
ingredients,
43%
Defects in
counterfeit
antibiotics
Bad quality,
24%
Weakly
dosed, 21%
Wrong active
ingredients, 7%
Bad packaging, 5%
Delepierre A, et al. Med Mal Infect. 2012;42(6)247-255.
Appropriate use of antibiotics
Counterfeit antibiotics are very common in Asia
Appropriate use of antibiotics
Appropriate use of antibiotics is urgent and critical
Antimicrobial stewardship
Practice guidelines for
major infections
Policies & regulations to
control and monitor
antibiotic use
R & D of novel antibiotics
Policy & regulation
National & international regulation is urgently required
• Legal control of antibiotic
supply, distribution and sales
• Public-private collaboration for
surveillance of AMR
• Awareness campaign for
general public & HCP
National priority
• Development of international
surveillance system
• Awareness campaign
• International collaboration for
control and prevention of AMR
International initiatives
Policies and regulations
Surveillance of AMR
Increased
awareness
Appropriate
antibiotic use
Infection
prevention &
control
Vaccination
Control and prevention of AMR
APEC economies should collaborate to combat AMR
- Johann Wolfgang Goethe
“Knowing is not enough, we must apply
Willing is not enough, we must do”

More Related Content

What's hot

Surveillance & IDSP
Surveillance & IDSPSurveillance & IDSP
Surveillance & IDSP
Dipayan Banerjee
 
Ensuring continuity of essential health services: A critical priority during ...
Ensuring continuity of essential health services: A critical priority during ...Ensuring continuity of essential health services: A critical priority during ...
Ensuring continuity of essential health services: A critical priority during ...
WHO Regional Office for the Eastern Mediterranean
 
Presentation – Action plan for the health sector response to viral hepatitis
Presentation – Action plan for the health sector response to viral hepatitis Presentation – Action plan for the health sector response to viral hepatitis
Presentation – Action plan for the health sector response to viral hepatitis
WHO Regional Office for Europe
 
Ending the pandemic; preventing future health emergencies
Ending the pandemic; preventing future health emergenciesEnding the pandemic; preventing future health emergencies
Ending the pandemic; preventing future health emergencies
WHO Regional Office for the Eastern Mediterranean
 
Introduction to Regional Director's annual report
Introduction to Regional Director's annual reportIntroduction to Regional Director's annual report
Introduction to Regional Director's annual report
WHO Regional Office for the Eastern Mediterranean
 
Nicolas Isla: Action Plan to improve public health preparedness and response ...
Nicolas Isla: Action Plan to improve public health preparedness and response ...Nicolas Isla: Action Plan to improve public health preparedness and response ...
Nicolas Isla: Action Plan to improve public health preparedness and response ...
THL
 
Rebecca Katz: Challenges in Global Health Security
Rebecca Katz: Challenges in Global Health SecurityRebecca Katz: Challenges in Global Health Security
Rebecca Katz: Challenges in Global Health Security
THL
 
Phase 4 Individual Project
Phase 4 Individual ProjectPhase 4 Individual Project
Phase 4 Individual Project
finman84
 
Health policy plan. 2007-lönnroth-156-66
Health policy plan. 2007-lönnroth-156-66Health policy plan. 2007-lönnroth-156-66
Health policy plan. 2007-lönnroth-156-66
Reaksmey Pe
 
Impact and cost effectivene of rotavirus vaccine introduction in afghanistan
Impact and cost   effectivene of  rotavirus vaccine  introduction in afghanistanImpact and cost   effectivene of  rotavirus vaccine  introduction in afghanistan
Impact and cost effectivene of rotavirus vaccine introduction in afghanistan
Najibullah Safi
 
World Health Day 2011
World Health Day 2011World Health Day 2011
World Health Day 2011
mediconerd
 
Whd amr
Whd amrWhd amr
Whd amr
joyjaikar1
 
Clare Hague PhD, Pharma & Health Conference 2021
Clare Hague PhD, Pharma & Health Conference 2021Clare Hague PhD, Pharma & Health Conference 2021
Clare Hague PhD, Pharma & Health Conference 2021
Starttech Ventures
 
COVID-19 Health System Response Monitor: Japan
COVID-19 Health System Response Monitor: JapanCOVID-19 Health System Response Monitor: Japan
COVID-19 Health System Response Monitor: Japan
Asia Pacific Observatory on Health Systems and Policies (APO)
 
Presentation –WHO Health Emergencies Programme: progress in the European Region
Presentation –WHO Health Emergencies Programme: progress in the European RegionPresentation –WHO Health Emergencies Programme: progress in the European Region
Presentation –WHO Health Emergencies Programme: progress in the European Region
WHO Regional Office for Europe
 
Presentation –Action plan for the health sector response to HIV
Presentation –Action plan for the health sector response to HIV Presentation –Action plan for the health sector response to HIV
Presentation –Action plan for the health sector response to HIV
WHO Regional Office for Europe
 
Regional strategy to improve access to medicines and vaccines in the Eastern ...
Regional strategy to improve access to medicines and vaccines in the Eastern ...Regional strategy to improve access to medicines and vaccines in the Eastern ...
Regional strategy to improve access to medicines and vaccines in the Eastern ...
WHO Regional Office for the Eastern Mediterranean
 
APO Independent State of Papua New Guinea Health System Review (Health in Tra...
APO Independent State of Papua New Guinea Health System Review (Health in Tra...APO Independent State of Papua New Guinea Health System Review (Health in Tra...
APO Independent State of Papua New Guinea Health System Review (Health in Tra...
Asia Pacific Observatory on Health Systems and Policies (APO)
 
COUNTDOWN Louis Niessen - Launch 2015
COUNTDOWN Louis Niessen - Launch 2015COUNTDOWN Louis Niessen - Launch 2015
COUNTDOWN Louis Niessen - Launch 2015
COUNTDOWN on NTDs
 
Michael Craig - Updates from the CDC
Michael Craig - Updates from the CDCMichael Craig - Updates from the CDC
Michael Craig - Updates from the CDC
John Blue
 

What's hot (20)

Surveillance & IDSP
Surveillance & IDSPSurveillance & IDSP
Surveillance & IDSP
 
Ensuring continuity of essential health services: A critical priority during ...
Ensuring continuity of essential health services: A critical priority during ...Ensuring continuity of essential health services: A critical priority during ...
Ensuring continuity of essential health services: A critical priority during ...
 
Presentation – Action plan for the health sector response to viral hepatitis
Presentation – Action plan for the health sector response to viral hepatitis Presentation – Action plan for the health sector response to viral hepatitis
Presentation – Action plan for the health sector response to viral hepatitis
 
Ending the pandemic; preventing future health emergencies
Ending the pandemic; preventing future health emergenciesEnding the pandemic; preventing future health emergencies
Ending the pandemic; preventing future health emergencies
 
Introduction to Regional Director's annual report
Introduction to Regional Director's annual reportIntroduction to Regional Director's annual report
Introduction to Regional Director's annual report
 
Nicolas Isla: Action Plan to improve public health preparedness and response ...
Nicolas Isla: Action Plan to improve public health preparedness and response ...Nicolas Isla: Action Plan to improve public health preparedness and response ...
Nicolas Isla: Action Plan to improve public health preparedness and response ...
 
Rebecca Katz: Challenges in Global Health Security
Rebecca Katz: Challenges in Global Health SecurityRebecca Katz: Challenges in Global Health Security
Rebecca Katz: Challenges in Global Health Security
 
Phase 4 Individual Project
Phase 4 Individual ProjectPhase 4 Individual Project
Phase 4 Individual Project
 
Health policy plan. 2007-lönnroth-156-66
Health policy plan. 2007-lönnroth-156-66Health policy plan. 2007-lönnroth-156-66
Health policy plan. 2007-lönnroth-156-66
 
Impact and cost effectivene of rotavirus vaccine introduction in afghanistan
Impact and cost   effectivene of  rotavirus vaccine  introduction in afghanistanImpact and cost   effectivene of  rotavirus vaccine  introduction in afghanistan
Impact and cost effectivene of rotavirus vaccine introduction in afghanistan
 
World Health Day 2011
World Health Day 2011World Health Day 2011
World Health Day 2011
 
Whd amr
Whd amrWhd amr
Whd amr
 
Clare Hague PhD, Pharma & Health Conference 2021
Clare Hague PhD, Pharma & Health Conference 2021Clare Hague PhD, Pharma & Health Conference 2021
Clare Hague PhD, Pharma & Health Conference 2021
 
COVID-19 Health System Response Monitor: Japan
COVID-19 Health System Response Monitor: JapanCOVID-19 Health System Response Monitor: Japan
COVID-19 Health System Response Monitor: Japan
 
Presentation –WHO Health Emergencies Programme: progress in the European Region
Presentation –WHO Health Emergencies Programme: progress in the European RegionPresentation –WHO Health Emergencies Programme: progress in the European Region
Presentation –WHO Health Emergencies Programme: progress in the European Region
 
Presentation –Action plan for the health sector response to HIV
Presentation –Action plan for the health sector response to HIV Presentation –Action plan for the health sector response to HIV
Presentation –Action plan for the health sector response to HIV
 
Regional strategy to improve access to medicines and vaccines in the Eastern ...
Regional strategy to improve access to medicines and vaccines in the Eastern ...Regional strategy to improve access to medicines and vaccines in the Eastern ...
Regional strategy to improve access to medicines and vaccines in the Eastern ...
 
APO Independent State of Papua New Guinea Health System Review (Health in Tra...
APO Independent State of Papua New Guinea Health System Review (Health in Tra...APO Independent State of Papua New Guinea Health System Review (Health in Tra...
APO Independent State of Papua New Guinea Health System Review (Health in Tra...
 
COUNTDOWN Louis Niessen - Launch 2015
COUNTDOWN Louis Niessen - Launch 2015COUNTDOWN Louis Niessen - Launch 2015
COUNTDOWN Louis Niessen - Launch 2015
 
Michael Craig - Updates from the CDC
Michael Craig - Updates from the CDCMichael Craig - Updates from the CDC
Michael Craig - Updates from the CDC
 

Similar to 2.3 overview of emerging infectious disease issues in the asia pacific region apa

World health day 2011
World health day  2011World health day  2011
World health day 2011
sarath3347
 
Dr. Tom Chiller - International Activities in Antimicrobial Resistance
Dr. Tom Chiller - International Activities in Antimicrobial ResistanceDr. Tom Chiller - International Activities in Antimicrobial Resistance
Dr. Tom Chiller - International Activities in Antimicrobial Resistance
John Blue
 
WHO - AMR Global Overview and Action Plan
WHO - AMR Global Overview and Action PlanWHO - AMR Global Overview and Action Plan
WHO - AMR Global Overview and Action Plan
markovingian
 
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan NkeckGlobal response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
J-réné Nkeck
 
Very final word litrature.docx
Very final word litrature.docxVery final word litrature.docx
Very final word litrature.docx
keneanmelkamu
 
Resistencia antimicroviana
Resistencia antimicrovianaResistencia antimicroviana
Resistencia antimicroviana
Lic en Enfermeria Zamudio
 
emerging and re-emerging vector borne diseases
emerging and re-emerging vector borne diseasesemerging and re-emerging vector borne diseases
emerging and re-emerging vector borne diseases
Anil kumar
 
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
AIDSTAROne
 
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
Sketchpowder, Inc.
 
WGHA Discovery Series: David Heymann
WGHA Discovery Series: David HeymannWGHA Discovery Series: David Heymann
WGHA Discovery Series: David Heymann
UWGlobalHealth
 
2018: FIND AMR Strategy
2018: FIND AMR Strategy2018: FIND AMR Strategy
2018: FIND AMR Strategy
SystemOne
 
publication_MlOA9_Situation Analysis
publication_MlOA9_Situation Analysispublication_MlOA9_Situation Analysis
publication_MlOA9_Situation Analysis
Saba Danawala
 
Global and National Action Plan on Anti-Microbial Resistance
Global and National Action Plan on Anti-Microbial ResistanceGlobal and National Action Plan on Anti-Microbial Resistance
Global and National Action Plan on Anti-Microbial Resistance
Zaid Wani
 
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a VaccineIFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
International Federation of Pharmaceutical Manufacturers & Associations (IFPMA)
 
Health Care workers; taking the lead and helping to fight antimicrobial resi...
Health Care workers; taking the lead and  helping to fight antimicrobial resi...Health Care workers; taking the lead and  helping to fight antimicrobial resi...
Health Care workers; taking the lead and helping to fight antimicrobial resi...
adewolepelumi
 
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERMEHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
Camilla d'Angelo
 
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERMEHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
Tímea Rezi-Kató
 
3.1 francois dabis
3.1 francois dabis3.1 francois dabis
3.1 francois dabis
Association LIR
 
Regional slides-jun-2014
Regional slides-jun-2014Regional slides-jun-2014
Regional slides-jun-2014
aidsdatahub
 
AMR seminar 4.3.23.pptx
AMR seminar 4.3.23.pptxAMR seminar 4.3.23.pptx
AMR seminar 4.3.23.pptx
DrYuktiBhandari
 

Similar to 2.3 overview of emerging infectious disease issues in the asia pacific region apa (20)

World health day 2011
World health day  2011World health day  2011
World health day 2011
 
Dr. Tom Chiller - International Activities in Antimicrobial Resistance
Dr. Tom Chiller - International Activities in Antimicrobial ResistanceDr. Tom Chiller - International Activities in Antimicrobial Resistance
Dr. Tom Chiller - International Activities in Antimicrobial Resistance
 
WHO - AMR Global Overview and Action Plan
WHO - AMR Global Overview and Action PlanWHO - AMR Global Overview and Action Plan
WHO - AMR Global Overview and Action Plan
 
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan NkeckGlobal response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
Global response to antimicrobial resistance, WHO, OIE, CDC summry. Jan Nkeck
 
Very final word litrature.docx
Very final word litrature.docxVery final word litrature.docx
Very final word litrature.docx
 
Resistencia antimicroviana
Resistencia antimicrovianaResistencia antimicroviana
Resistencia antimicroviana
 
emerging and re-emerging vector borne diseases
emerging and re-emerging vector borne diseasesemerging and re-emerging vector borne diseases
emerging and re-emerging vector borne diseases
 
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
AIDSTAR-One WHO's 2010 Recommendations for HIV Treatment: National Guideline ...
 
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
The Indonesian response for the HIV/AIDS Epidemic among and from Injecting Dr...
 
WGHA Discovery Series: David Heymann
WGHA Discovery Series: David HeymannWGHA Discovery Series: David Heymann
WGHA Discovery Series: David Heymann
 
2018: FIND AMR Strategy
2018: FIND AMR Strategy2018: FIND AMR Strategy
2018: FIND AMR Strategy
 
publication_MlOA9_Situation Analysis
publication_MlOA9_Situation Analysispublication_MlOA9_Situation Analysis
publication_MlOA9_Situation Analysis
 
Global and National Action Plan on Anti-Microbial Resistance
Global and National Action Plan on Anti-Microbial ResistanceGlobal and National Action Plan on Anti-Microbial Resistance
Global and National Action Plan on Anti-Microbial Resistance
 
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a VaccineIFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
IFPMA: From Manufacturing to the Vaccinee – the Complex Journey of a Vaccine
 
Health Care workers; taking the lead and helping to fight antimicrobial resi...
Health Care workers; taking the lead and  helping to fight antimicrobial resi...Health Care workers; taking the lead and  helping to fight antimicrobial resi...
Health Care workers; taking the lead and helping to fight antimicrobial resi...
 
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERMEHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
 
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERMEHP_PAPERS_2016_AntimicrobialResistance_SCHERM
EHP_PAPERS_2016_AntimicrobialResistance_SCHERM
 
3.1 francois dabis
3.1 francois dabis3.1 francois dabis
3.1 francois dabis
 
Regional slides-jun-2014
Regional slides-jun-2014Regional slides-jun-2014
Regional slides-jun-2014
 
AMR seminar 4.3.23.pptx
AMR seminar 4.3.23.pptxAMR seminar 4.3.23.pptx
AMR seminar 4.3.23.pptx
 

More from sandraduhrkopp

Careersdonewrite m fhighrise
Careersdonewrite m fhighriseCareersdonewrite m fhighrise
Careersdonewrite m fhighrise
sandraduhrkopp
 
Med errors apa
Med errors  apaMed errors  apa
Med errors apa
sandraduhrkopp
 
Needle free systems
Needle free systemsNeedle free systems
Needle free systems
sandraduhrkopp
 
Slides
SlidesSlides
Food presentation
Food presentationFood presentation
Food presentation
sandraduhrkopp
 
Presentation workshop
Presentation workshopPresentation workshop
Presentation workshop
sandraduhrkopp
 
presentation project management
presentation   project managementpresentation   project management
presentation project management
sandraduhrkopp
 
short presentation
short presentationshort presentation
short presentation
sandraduhrkopp
 
Jackie reco
Jackie recoJackie reco
Jackie reco
sandraduhrkopp
 
Spsp3
Spsp3Spsp3
Spsp2
Spsp2Spsp2
Wlm2
Wlm2Wlm2
Spare parts codification slides2
Spare parts codification slides2Spare parts codification slides2
Spare parts codification slides2
sandraduhrkopp
 
Wlm
WlmWlm
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
sandraduhrkopp
 
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
sandraduhrkopp
 
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
sandraduhrkopp
 
Keenethrecomm
KeenethrecommKeenethrecomm
Keenethrecomm
sandraduhrkopp
 
Cares word
Cares wordCares word
Cares word
sandraduhrkopp
 
Tcr@bpl patio 2012
Tcr@bpl patio 2012Tcr@bpl patio 2012
Tcr@bpl patio 2012
sandraduhrkopp
 

More from sandraduhrkopp (20)

Careersdonewrite m fhighrise
Careersdonewrite m fhighriseCareersdonewrite m fhighrise
Careersdonewrite m fhighrise
 
Med errors apa
Med errors  apaMed errors  apa
Med errors apa
 
Needle free systems
Needle free systemsNeedle free systems
Needle free systems
 
Slides
SlidesSlides
Slides
 
Food presentation
Food presentationFood presentation
Food presentation
 
Presentation workshop
Presentation workshopPresentation workshop
Presentation workshop
 
presentation project management
presentation   project managementpresentation   project management
presentation project management
 
short presentation
short presentationshort presentation
short presentation
 
Jackie reco
Jackie recoJackie reco
Jackie reco
 
Spsp3
Spsp3Spsp3
Spsp3
 
Spsp2
Spsp2Spsp2
Spsp2
 
Wlm2
Wlm2Wlm2
Wlm2
 
Spare parts codification slides2
Spare parts codification slides2Spare parts codification slides2
Spare parts codification slides2
 
Wlm
WlmWlm
Wlm
 
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
 
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
 
Kenneth recom
Kenneth recomKenneth recom
Kenneth recom
 
Keenethrecomm
KeenethrecommKeenethrecomm
Keenethrecomm
 
Cares word
Cares wordCares word
Cares word
 
Tcr@bpl patio 2012
Tcr@bpl patio 2012Tcr@bpl patio 2012
Tcr@bpl patio 2012
 

Recently uploaded

220711130097 Tulip Samanta Concept of Information and Communication Technology
220711130097 Tulip Samanta Concept of Information and Communication Technology220711130097 Tulip Samanta Concept of Information and Communication Technology
220711130097 Tulip Samanta Concept of Information and Communication Technology
Kalna College
 
Cross-Cultural Leadership and Communication
Cross-Cultural Leadership and CommunicationCross-Cultural Leadership and Communication
Cross-Cultural Leadership and Communication
MattVassar1
 
Non-Verbal Communication for Tech Professionals
Non-Verbal Communication for Tech ProfessionalsNon-Verbal Communication for Tech Professionals
Non-Verbal Communication for Tech Professionals
MattVassar1
 
(T.L.E.) Agriculture: "Ornamental Plants"
(T.L.E.) Agriculture: "Ornamental Plants"(T.L.E.) Agriculture: "Ornamental Plants"
(T.L.E.) Agriculture: "Ornamental Plants"
MJDuyan
 
Observational Learning
Observational Learning Observational Learning
Observational Learning
sanamushtaq922
 
managing Behaviour in early childhood education.pptx
managing Behaviour in early childhood education.pptxmanaging Behaviour in early childhood education.pptx
managing Behaviour in early childhood education.pptx
nabaegha
 
The Science of Learning: implications for modern teaching
The Science of Learning: implications for modern teachingThe Science of Learning: implications for modern teaching
The Science of Learning: implications for modern teaching
Derek Wenmoth
 
Creating Images and Videos through AI.pptx
Creating Images and Videos through AI.pptxCreating Images and Videos through AI.pptx
Creating Images and Videos through AI.pptx
Forum of Blended Learning
 
220711130100 udita Chakraborty Aims and objectives of national policy on inf...
220711130100 udita Chakraborty  Aims and objectives of national policy on inf...220711130100 udita Chakraborty  Aims and objectives of national policy on inf...
220711130100 udita Chakraborty Aims and objectives of national policy on inf...
Kalna College
 
220711130088 Sumi Basak Virtual University EPC 3.pptx
220711130088 Sumi Basak Virtual University EPC 3.pptx220711130088 Sumi Basak Virtual University EPC 3.pptx
220711130088 Sumi Basak Virtual University EPC 3.pptx
Kalna College
 
Erasmus + DISSEMINATION ACTIVITIES Croatia
Erasmus + DISSEMINATION ACTIVITIES CroatiaErasmus + DISSEMINATION ACTIVITIES Croatia
Erasmus + DISSEMINATION ACTIVITIES Croatia
whatchangedhowreflec
 
Post init hook in the odoo 17 ERP Module
Post init hook in the  odoo 17 ERP ModulePost init hook in the  odoo 17 ERP Module
Post init hook in the odoo 17 ERP Module
Celine George
 
nutrition in plants chapter 1 class 7...
nutrition in plants chapter 1 class 7...nutrition in plants chapter 1 class 7...
nutrition in plants chapter 1 class 7...
chaudharyreet2244
 
Contiguity Of Various Message Forms - Rupam Chandra.pptx
Contiguity Of Various Message Forms - Rupam Chandra.pptxContiguity Of Various Message Forms - Rupam Chandra.pptx
Contiguity Of Various Message Forms - Rupam Chandra.pptx
Kalna College
 
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptx
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptxScience-9-Lesson-1-The Bohr Model-NLC.pptx pptx
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptx
Catherine Dela Cruz
 
Brand Guideline of Bashundhara A4 Paper - 2024
Brand Guideline of Bashundhara A4 Paper - 2024Brand Guideline of Bashundhara A4 Paper - 2024
Brand Guideline of Bashundhara A4 Paper - 2024
khabri85
 
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
Nguyen Thanh Tu Collection
 
Information and Communication Technology in Education
Information and Communication Technology in EducationInformation and Communication Technology in Education
Information and Communication Technology in Education
MJDuyan
 
A Quiz on Drug Abuse Awareness by Quizzito
A Quiz on Drug Abuse Awareness by QuizzitoA Quiz on Drug Abuse Awareness by Quizzito
A Quiz on Drug Abuse Awareness by Quizzito
Quizzito The Quiz Society of Gargi College
 
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptxCapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapitolTechU
 

Recently uploaded (20)

220711130097 Tulip Samanta Concept of Information and Communication Technology
220711130097 Tulip Samanta Concept of Information and Communication Technology220711130097 Tulip Samanta Concept of Information and Communication Technology
220711130097 Tulip Samanta Concept of Information and Communication Technology
 
Cross-Cultural Leadership and Communication
Cross-Cultural Leadership and CommunicationCross-Cultural Leadership and Communication
Cross-Cultural Leadership and Communication
 
Non-Verbal Communication for Tech Professionals
Non-Verbal Communication for Tech ProfessionalsNon-Verbal Communication for Tech Professionals
Non-Verbal Communication for Tech Professionals
 
(T.L.E.) Agriculture: "Ornamental Plants"
(T.L.E.) Agriculture: "Ornamental Plants"(T.L.E.) Agriculture: "Ornamental Plants"
(T.L.E.) Agriculture: "Ornamental Plants"
 
Observational Learning
Observational Learning Observational Learning
Observational Learning
 
managing Behaviour in early childhood education.pptx
managing Behaviour in early childhood education.pptxmanaging Behaviour in early childhood education.pptx
managing Behaviour in early childhood education.pptx
 
The Science of Learning: implications for modern teaching
The Science of Learning: implications for modern teachingThe Science of Learning: implications for modern teaching
The Science of Learning: implications for modern teaching
 
Creating Images and Videos through AI.pptx
Creating Images and Videos through AI.pptxCreating Images and Videos through AI.pptx
Creating Images and Videos through AI.pptx
 
220711130100 udita Chakraborty Aims and objectives of national policy on inf...
220711130100 udita Chakraborty  Aims and objectives of national policy on inf...220711130100 udita Chakraborty  Aims and objectives of national policy on inf...
220711130100 udita Chakraborty Aims and objectives of national policy on inf...
 
220711130088 Sumi Basak Virtual University EPC 3.pptx
220711130088 Sumi Basak Virtual University EPC 3.pptx220711130088 Sumi Basak Virtual University EPC 3.pptx
220711130088 Sumi Basak Virtual University EPC 3.pptx
 
Erasmus + DISSEMINATION ACTIVITIES Croatia
Erasmus + DISSEMINATION ACTIVITIES CroatiaErasmus + DISSEMINATION ACTIVITIES Croatia
Erasmus + DISSEMINATION ACTIVITIES Croatia
 
Post init hook in the odoo 17 ERP Module
Post init hook in the  odoo 17 ERP ModulePost init hook in the  odoo 17 ERP Module
Post init hook in the odoo 17 ERP Module
 
nutrition in plants chapter 1 class 7...
nutrition in plants chapter 1 class 7...nutrition in plants chapter 1 class 7...
nutrition in plants chapter 1 class 7...
 
Contiguity Of Various Message Forms - Rupam Chandra.pptx
Contiguity Of Various Message Forms - Rupam Chandra.pptxContiguity Of Various Message Forms - Rupam Chandra.pptx
Contiguity Of Various Message Forms - Rupam Chandra.pptx
 
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptx
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptxScience-9-Lesson-1-The Bohr Model-NLC.pptx pptx
Science-9-Lesson-1-The Bohr Model-NLC.pptx pptx
 
Brand Guideline of Bashundhara A4 Paper - 2024
Brand Guideline of Bashundhara A4 Paper - 2024Brand Guideline of Bashundhara A4 Paper - 2024
Brand Guideline of Bashundhara A4 Paper - 2024
 
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
BỘ BÀI TẬP TEST THEO UNIT - FORM 2025 - TIẾNG ANH 12 GLOBAL SUCCESS - KÌ 1 (B...
 
Information and Communication Technology in Education
Information and Communication Technology in EducationInformation and Communication Technology in Education
Information and Communication Technology in Education
 
A Quiz on Drug Abuse Awareness by Quizzito
A Quiz on Drug Abuse Awareness by QuizzitoA Quiz on Drug Abuse Awareness by Quizzito
A Quiz on Drug Abuse Awareness by Quizzito
 
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptxCapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
CapTechTalks Webinar Slides June 2024 Donovan Wright.pptx
 

2.3 overview of emerging infectious disease issues in the asia pacific region apa

  • 1. Alessandro Pontes-Arruda,LLB, MD, MSc, PhD, FCCM Overview of emerging infectious disease issues in the Asia Pacific region Antimicrobial resistance (AMR) & Healthcare associated infection (HAI)
  • 2. Bugs strike back ! Global crisis of AMR TIME magazine (June 26, 2006)
  • 3. Molton JS, et al. Clin Infect Dis 2013 doi: 10.1093/cid/cit020. NDM-1 positive Enterobacteriaceae Boston 2010 Guatemala 2011 UK 2009 Sweden 2008 Singapore 2011 Japan 2009 Sydney 2010 Kenya 2009 South Africa 2011 India 2008 KPC positive Klebsiella pneumoniae North Carolina 1996 UK 2009 Greece 2007 Israel 2004 South Africa 2011 China 2004 Singapore 2010 Sydney 2010 Colombia 2008 Brazil & Argentina 2008 Global crisis of AMR AMR is an emerging infectious disease that spreads globally
  • 4. WHO and WEF highlight the clinical and economic risk* of AMR Impact of AMR Antimicrobial resistance ; Global report on surveillance, World Health Organization (WHO), April 2014 ; World Economic Forum. Global Risks 2013. 8th Ed. & 2014, 9th Ed. * Losses to GDP : 0.4 ~ 1.6 %
  • 5. Major examples of AMR Asia is an epicenter of AMR in most bacterial pathogens * Highest reported prevalence of resistance to prototype antibiotics, + CAP : community-acquired pneumonia, HAP : Hospital-acquired pneumonia Community pathogen Disease Antibiotic % resistance* Focus area S. pneumoniae CAP+ Macrolide 73% Asia E. coli UTI 3rd Cephalosporins 95% Asia S. typhi Enteric infection Ciprofloxacin 84% Asia Hospital pathogen Disease Antibiotic % resistance* Focus area S. aureus HAP+, bacteremia Methicillin 82% Asia E. coli HAP, bacteremia Ciprofloxacin 96% Asia K. pneumoniae HAP, bacteremia 3rd Cephalosporins 81% Asia P. aeruginosa HAP Carbapenem 30% Asia A. baumanii HAP Carbapenem 68% Asia WHO, Antimicrobial Resistance : Global report on surveillance. 2014; Kim SH, et al. AAC, 2012;56(3):1418-26; Chung DR, et al. Am J Respir Crit Care Med. 2011;184(12):1409-17; Singhal L, et al. Indian J Med Microbiol. 2014;32(2):149-52
  • 6. Global strategy to combat AMR APEC has been focusing on AMR since 2010 “International campaign program to control AMR in the AP region”2nd project (2012-2013) “International initiatives to control AMR in the AP region”1st project (2010-2011) “APEC symposium on control and prevention of AMR”3rd project (2013) “Implementation of international Campaign program to control AMR”4th project (2014)
  • 7. Control of AMR Surveillance of AMR and antibiotic use Infection control Increased awareness Appropriate use of antibiotics Policy & regulation Vaccination APEC strategy to combat AMR APEC AMR projects proposed six major action plans
  • 8. Song JH. APEC project : International initiatives to control AMR. 2011. Country Program Year of established 14 countries Asian Network for Surveillance of Resistant Pathogens (ANSORP) 1996 Korea  Korean Network for Studies on Infectious Diseases (KONSID)  Korean Nationwide Surveillance of Antimicrobial Resistance (KONSAR) 1997 China Ministry of Health National Antimicrobial Resistance Surveillance Net (Mohnarin) 2004 Japan Japanese Nosocomial Infection Surveillance (JANIS) 2000 Malaysia Malaysia Antibiotic Resistant Surveillance Program (MARSP) 1990 Philippines National antimicrobial resistance surveillance program 1988 Singapore The Network for Antimicrobial Resistance Surveillance Taiwan Taiwan Nosocomial Infections Surveillance System (TNIS) 2007 Thailand  National Antimicrobial Resistance Surveillance of Thailand (NARST) Surveillance of AMR in AP region There are a few surveillance programs in the region
  • 9. Song JH. APEC project : International initiatives to control AMR. 2011. Surveillance of AMR in AP region ANSORP is the representative international system in Asia Organizer : Jae-Hoon Song Headquarter : Samsung Medical Center Local Network Organizers (LNO) ANSORP Member Hospitals Principal & co-investigators Local ANSORP Networks (LAN) Headquarter Japan India Thailand Vietnam Hong Kong China Philippines Taiwan Malaysia Singapore Indonesia Sri Lanka Saudi Arabia Korea 14 countries/area 65 cities, 111 hospitals, 201 investigators
  • 10. Surveillance of AMR in AP region There are major hurdles of AMR surveillance in AP region Lack of awareness about impact of AMR Lack of laboratory capacity and standard platform Limited funding and human resources Lack of national and regional coordination
  • 11. No international program in Asian countries Awareness of AMR Antibiotic awareness campaign is urgently needed
  • 12. Professional society / Government Awareness of AMR Campaign 4 is a new international awareness campaign in Asia
  • 13. Awareness of AMR Campaign 4 will be introduced to Asia Website : www.campaign4.org / www.icareproject.org
  • 14. Van Boeckel TP, et al. Lancet Infect Dis. 2014. S1473-3099(14)70780-7. Appropriate use of antibiotics Asia showed increased antibiotic consumption (2000 to 2010)
  • 15. • Antibiotics account for 28% of global counterfeit drugs - Counterfeit antibiotics account for 5% of global antibiotic market • 78% of them were made in SE Asia • 44% of them were consumed in SE Asia Counterfeit antibiotic use South-East Asia, 44% Sub-Saharan Africa, 30% Europe & North America, 9% Others, 17% No active ingredients, 43% Defects in counterfeit antibiotics Bad quality, 24% Weakly dosed, 21% Wrong active ingredients, 7% Bad packaging, 5% Delepierre A, et al. Med Mal Infect. 2012;42(6)247-255. Appropriate use of antibiotics Counterfeit antibiotics are very common in Asia
  • 16. Appropriate use of antibiotics Appropriate use of antibiotics is urgent and critical Antimicrobial stewardship Practice guidelines for major infections Policies & regulations to control and monitor antibiotic use R & D of novel antibiotics
  • 17. Policy & regulation National & international regulation is urgently required • Legal control of antibiotic supply, distribution and sales • Public-private collaboration for surveillance of AMR • Awareness campaign for general public & HCP National priority • Development of international surveillance system • Awareness campaign • International collaboration for control and prevention of AMR International initiatives
  • 18. Policies and regulations Surveillance of AMR Increased awareness Appropriate antibiotic use Infection prevention & control Vaccination Control and prevention of AMR APEC economies should collaborate to combat AMR
  • 19. - Johann Wolfgang Goethe “Knowing is not enough, we must apply Willing is not enough, we must do”

Editor's Notes

  1. 그림 설명 : The earliest reported cases in each continent are shown. Arrows indicate the significant international movements of these organisms
  翻译: