Introduction: In an interconnected world where the boundaries between humans, and animals. and the environment blurred. One Health has emerged as a comprehensive approach to addressing complex health challenges. One Health recognizes the intricate connections between the Health of humans and animals. and ecosystems, emphasizing the need for collaborative efforts across disciplines to achieve optimal well-being for all. This article delves into the fundamental principles of It, and its historical roots. and its potential to revolutionize the way we approach global Health. Follow us on: Pinterest Understanding One Health: A- Definition and Scope: It is an integrative approach that considers the Health of humans, animals. and the environment as interdependent entities. It acknowledges that the Health of one component influences the Health of the others. and disruptions in any of these systems can have far-reaching consequences. This approach goes beyond traditional silos in health management. and embraces a holistic perspective. recognizing the intricate web of connections that shape our Health. B- Historical Roots: The roots of the It concept can traced back to ancient civilizations. where the interconnectedness of human and animal health acknowledged. But, the formal recognition of It as a distinct field gained momentum in the late 20th century. The emergence of zoonotic diseases transmitted between animals. and humans highlighted the need for a collaborative approach to disease prevention and control. Key Principles of One Health: A- Interdisciplinary Collaboration: At the heart of It is interdisciplinary collaboration. This principle involves breaking down the traditional barriers between medical, veterinary. and environmental sciences. Professionals from various fields work together to understand the complex dynamics of Health. and to develop effective strategies for prevention, surveillance, and response to emerging threats. B- Zoonotic Disease Surveillance: Given the increasing frequency of zoonotic disease outbreaks. It emphasizes surveillance and early detection. Monitoring diseases at the human-animal-environment interface is crucial for identifying potential threats before. they escalate into global pandemics. This proactive approach involves close collaboration between public health agencies. veterinary services, and environmental monitoring bodies. C- Environmental Stewardship: It recognizes the impact of environmental degradation on Health. Climate change, deforestation, and pollution can exacerbate the spread of diseases. affect water and food sources, and compromise the well-being of ecosystems. Integrating environmental stewardship into health policies is essential for safeguarding the Health of present and future generations. Examples of One Health in Action: A- Pandemic Preparedness: The ongoing COVID-19 pandemic has underscored the importance of a It approach. The virus, believed to have originated in bats.