Autonomous systems can help address challenges posed by COVID-19 in several ways: 1) Drones can monitor social distancing and enforce mask-wearing while also detecting infectious conditions through sensors and cameras. 2) Autonomous vehicles can provide contact-less transportation of goods during the outbreak. 3) Robots are being developed for throat swabbing tests to reduce risk to healthcare workers and enhance testing capacity. 4) Autonomous robots using UV light can disinfect surfaces to help overwhelmed hospitals.