This document discusses the management and control of important transboundary animal diseases in Malaysia. It focuses on five major diseases of concern: foot and mouth disease, contagious bovine pleuropneumonia, highly pathogenic avian influenza, Newcastle disease, and African and classical swine fever. Highly pathogenic avian influenza first occurred in Malaysia in 2004, with a total of 18 outbreaks through 2007 that were successfully eradicated using a stamping out policy with full compensation. Malaysia also recently lost its rabies-free status due to a 2015 outbreak, though there were no reported human cases despite dog bites. Currently, Malaysia uses a sub-dermal RFID-based system for animal identification, monitoring, and traceability.