Zaiyang Li discusses the technology stack for a project, including the front-end framework Angular and build tools like Webpack, and the back-end framework ASP.NET Core with libraries like Dapper and testing tools like Xunit and Moq. Chart.js is used for data visualization, and a bespoke event sourcing framework is in active development to run in the same process as the web server. Protocol buffers are used for serialization and provide benefits like high performance and backward compatibility.