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Score Co-
eff
Total
DISEASE KNOWLEDGE - 10
criteria
0 1 2 3 4
Speed of spread None
Non
transmissible
Very slow Low level of
transmission within holdings
and unlikely between
holdings
Slow
Slow transmission
between holdings
with or without
animal movements
Medium
Rapid transmission between
holdings with or without
animal movements
High
Rapid transmission
between holdings
without animal
movements
2.5
Number of livestock species involved One ND or expected to be
limited
Limited
2 species
Medium
3 species11
High
4 species and over
2.5
Persistence of the infectious agent in the
environment
No
Never Found
Rare Occasionally found ND if unknown Constant Animal reservoir
or vector
Not removable from
the environment
2.5
Risk of spread to susceptible
populations
No
Not
contagious
Low Transmissible direct
contact
ND if unknown Medium Indirect contact,
contagion
High
Airborne infection
2.5
Potential for silent spread None Negligible
Signs of infection easily
recognised and likely to
occur in animal under
supervision
Low
Signs of infection
easily recognised but
depends on the level
of supervision
Moderate
Specific diagnosis may be
difficult in one or more
species
High
Disease/infection not
likely to be detected
for some time
2.5
Wildlife reservoir and potential spread Negligible
No known
wildlife
reservoir
Minor Prevalence in remote
wildlife
Moderate Wildlife
reservoir: no direct
contact with humans
or domestic animals
Significant
Wildlife reservoir
Serious Wildlife
reservoir in close
contact with humans
and/or domestic
animals
2.5
Vector reservoir and potential spread None
No known
vector or
reservoir
Low
Competent vector(s) thought
to exist in the country but
not considered capable of
surviving and transmitting
infection
Medium
Competent vector(s)
exist in the country
but not considered
capable of surviving
and transmitting
infection
High
Competent vector(s) exist in
the country but not
considered capable of
surviving but could transmit
infection
Very High
Competent vector(s)
exist in the country
and is (are) capable
of surviving and
transmitting infection
2.5
Variability of the agent Negligible
One type,
stable
host/vector
Low
Few types, not mutating,
stable host/vector
Moderate
Few types, not
mutating, low host
specificity, stable
vector if any
High
Numerous types or
mutating, low host or vector
specificity
Very High
Numerous types and
mutating, low host or
vector specificity
2.5
Understanding of fundamental
immunology
Fully
understood,
both humoral
and cellular
immunity
Fully understand humoral
immunity and partial
understanding of cellular
immunity
Partially understand
humoral and cellular
immunity
Partially
understand humoral
immunity
None
Nothing known about
the immunology
2.5
Host-Pathogen interaction Fully
understand the
host-pathogen
interactions
Understand some aspects of
the host and pathogen
interactions
Partially understand
the host-pathogen
interactions
Little understanding of the
host-pathogen interactions
No information 2.5
IMPACT ON ANIMAL HEALTH
AND WELFARE - 3 criteria
0 1 2 3 4
Disease impact on production None
Production not
affected
Very low
Some loss of production but
no major impact on income
Low
Production reduced
by less than 20%.
Major loss of income
Medium
Production reduced by more
than 20%. Major loss of
income
Severe
Production reduced
by more than 50%.
Major loss of income
and viability of
industry threatened
8.33
Duration of animal welfare impact None
No impact
Transcient
Impact less than 48 hours
Short Term
48 hours to 13 days
Medium term
15 days to 24 months
Permanent
Greater than 24
months
8.33
Proportion of animal affected suffering
pain/ injury/ distress as a result of the
disease
None
No animal
affected
Very low
<5% of animals suffer
serious impact
Low
6-20% of animals
suffer serious impact
Medium
21 to 50% of animals suffer
serious impact
Serious
>50% of animals
suffer serious impact
8.33
IMPACT ON PUBLIC HEALTH -
HUMAN HEALTH - 6 criteria
0 1 2 3 4
Impact of occurence on human health None
Humans not
considered
susceptible to
infection
Mild
Symptoms mild, transcient
without lasting effects
Medium
Symptoms may
require time off
work, (1week) and/or
medical intervention
Serious Symptoms
often provoke medical
intervention, possible long
term health effects (>1
month). Extreme pain and
discomfort. Fatalities
uncommon
High
High case fatality
(>5%) and/or
permanent health
effects
4.16
Likelihood of occurence None Prov
en
impossibility
of
transmission
to humans
through live
animals,
animal
products,
vectors or
food
Extremely rare Probability
lower than 1/1000000
Occasional Occurs
at an incidence lower
than 1/10000
Regular Occurs at an
incidence lower than 1/1000
Frequent Occ
urs at an incidence
higher than 1/1000
4.16
Impact of occurrence on food safety No
Not spread in
food
Negligible
Very low level of
contamination of food but
unlikely to cause problems
Low
Low level of
contamination and
can cause
disease/infection if
organisms ingested in
large numbers
Medium Probability of
spread via food but large
numbers of organisms
needed to cause problems.
Precautions required
High
High probability of
spread via food,
small infective dose
and strict precautions
required
4.16
Transmissibility (spread from animal to
human)
No
No
transmission
possible
Negligible
No known transmission to
humans or no information
Low
Possible transmission
and existing contacts
with live animals
Medium
Possible transmission or
contamination through
direct or indirect contact or
vector/food
High
Very low species
barrier, possible
airborne or through
the environment
4.16
Spread in humans No
Non-
transmissible
Negligible
No known transmission
between humans or no
information
Low Transmission
between humans is
uncommon
Moderate Transmission
between humans requires
prolonged or high level
challenge
Rapid Trans
mission between
humans occurs
frequently and is
common
4.16
Bioterrorism potential None
Agent
unavailable or
impossible to
handle or no
harm
Negligible
Agent available but difficult
to handle or low potential
harm
Low
Agent available and
easy to handle by
pros and labs but low
potential harm
Medium
Agent available and easy to
handle by pros and labs and
high potential harm
Severe
Agent available and
easy to handle by
individuals and high
potential harm
4.16
IMPACT ON WIDER SOCIETY - 3
criteria
0 1 2 3 4
Economic direct impact (including
cumulative costs (e.g. Enzoonotic vs
Epizootic))
None
No loss, no
control
measures
Negligible
Minor reduction in
production
Low
Production reduced
but not banned.
Treatment and
vaccination
Medium
Production reduced and
partially banned. Test and
slaughter
High
Production reduced
and banned. Total
slaughter
8.33
Economic indirect impact (social,
market)
None
Products
continue to be
distributed
Negligible
Minor impact on
distribution of products
Low
Herd products
redirected to lower
value markets
Medium
Market price reduced
temporarily by less than
30%
High
Reduction by more
than 30% over a
month or a country
wide ban
8.33
Agriterrorism potential None
Agent
unavailable or
impossible to
handle or no
spread
Negligible
Agent available but difficult
to handle or low spread or
low economic damages
Low
Agent available and
easy to handle by
professionals and
labs but low spread
or low economic
damages
Medium
Agent available and easy to
handle by professionals and
labs and rapidly spread or
high economic damages
Severe
Agent available and
easy to handle by
individuals and
rapidly spread and
great economic
damages
8.33
IMPACT ON TRADE - 4 criteria 0 1 2 3 4
Impact on international trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or
a list of commodities,
no loss of official
status
Significant
Zone standstill, loss of
official status, short
recovery period
Serious
Possible nationwide
ban standstill with or
without list, official
atatus difficult to
recover
6.25
Impact on Economic trade due to
existing regulations
None
No restriction
or only at
animal level
Minor
Only at herd level
Moderate
At zone level and/or
list of commodities
Significant
At zone level and/or no list
of commodities
Serious
Nationwide
ban/standstill with or
without list
6.25
Potential for zoning High
Zoning
possible at
farm level
Moderate
Zoning possible 1 to 10 kms
Low
Zoning possible but
more than 10 kms
Very low
Zoning using wider
administrative boundaries
None
Only compartments
6.25
Impact on security of food supply Extremely
limited,
anecdotal
Low value
Only in some remote areas
Moderate
Someremote areas
may be temporarily
out of stock
High
Some areas of the country
may be out of stock
Very High
May cause or
increase hunger
problems
6.25
CONTROL TOOLS - 3 criteria 2 1 0 -1 -2
Appropriate diagnostics Need: Yes
Availability:
No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential:
Low to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes
(fully effective)
Market Potential: Yes
16.6
6
Appropriate vaccines Need: Yes
Availability:
No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Yes
Availability: Yes (not
fully effective)
Market Potential:
Low to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes
(fully effective)
Market Potential: Yes
16.6
6
Appropriate pharmaceuticals Need: Yes
Availability:
No
Market
Potential: Low
Need: Yes
Availability: No
Market Potential: Yes
Need: Bacteria - Yes
Need: Virus -
Desirable
Availability: Bacteria
- Yes (not fully
effective)
Availability: Virus -
No
Market Potential:
Low to Medium
Need: Yes
Availability: Yes (not fully
effective)
Market Potential: Yes
Either Need: No
or Need: Yes
Availability: Yes
(fully effective)
Market Potential: Yes
16.6
6
TOTAL

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Prioritization Tool

  • 1. Score Co- eff Total DISEASE KNOWLEDGE - 10 criteria 0 1 2 3 4 Speed of spread None Non transmissible Very slow Low level of transmission within holdings and unlikely between holdings Slow Slow transmission between holdings with or without animal movements Medium Rapid transmission between holdings with or without animal movements High Rapid transmission between holdings without animal movements 2.5 Number of livestock species involved One ND or expected to be limited Limited 2 species Medium 3 species11 High 4 species and over 2.5 Persistence of the infectious agent in the environment No Never Found Rare Occasionally found ND if unknown Constant Animal reservoir or vector Not removable from the environment 2.5 Risk of spread to susceptible populations No Not contagious Low Transmissible direct contact ND if unknown Medium Indirect contact, contagion High Airborne infection 2.5 Potential for silent spread None Negligible Signs of infection easily recognised and likely to occur in animal under supervision Low Signs of infection easily recognised but depends on the level of supervision Moderate Specific diagnosis may be difficult in one or more species High Disease/infection not likely to be detected for some time 2.5 Wildlife reservoir and potential spread Negligible No known wildlife reservoir Minor Prevalence in remote wildlife Moderate Wildlife reservoir: no direct contact with humans or domestic animals Significant Wildlife reservoir Serious Wildlife reservoir in close contact with humans and/or domestic animals 2.5
  • 2. Vector reservoir and potential spread None No known vector or reservoir Low Competent vector(s) thought to exist in the country but not considered capable of surviving and transmitting infection Medium Competent vector(s) exist in the country but not considered capable of surviving and transmitting infection High Competent vector(s) exist in the country but not considered capable of surviving but could transmit infection Very High Competent vector(s) exist in the country and is (are) capable of surviving and transmitting infection 2.5 Variability of the agent Negligible One type, stable host/vector Low Few types, not mutating, stable host/vector Moderate Few types, not mutating, low host specificity, stable vector if any High Numerous types or mutating, low host or vector specificity Very High Numerous types and mutating, low host or vector specificity 2.5 Understanding of fundamental immunology Fully understood, both humoral and cellular immunity Fully understand humoral immunity and partial understanding of cellular immunity Partially understand humoral and cellular immunity Partially understand humoral immunity None Nothing known about the immunology 2.5 Host-Pathogen interaction Fully understand the host-pathogen interactions Understand some aspects of the host and pathogen interactions Partially understand the host-pathogen interactions Little understanding of the host-pathogen interactions No information 2.5 IMPACT ON ANIMAL HEALTH AND WELFARE - 3 criteria 0 1 2 3 4 Disease impact on production None Production not affected Very low Some loss of production but no major impact on income Low Production reduced by less than 20%. Major loss of income Medium Production reduced by more than 20%. Major loss of income Severe Production reduced by more than 50%. Major loss of income and viability of industry threatened 8.33 Duration of animal welfare impact None No impact Transcient Impact less than 48 hours Short Term 48 hours to 13 days Medium term 15 days to 24 months Permanent Greater than 24 months 8.33
  • 3. Proportion of animal affected suffering pain/ injury/ distress as a result of the disease None No animal affected Very low <5% of animals suffer serious impact Low 6-20% of animals suffer serious impact Medium 21 to 50% of animals suffer serious impact Serious >50% of animals suffer serious impact 8.33 IMPACT ON PUBLIC HEALTH - HUMAN HEALTH - 6 criteria 0 1 2 3 4 Impact of occurence on human health None Humans not considered susceptible to infection Mild Symptoms mild, transcient without lasting effects Medium Symptoms may require time off work, (1week) and/or medical intervention Serious Symptoms often provoke medical intervention, possible long term health effects (>1 month). Extreme pain and discomfort. Fatalities uncommon High High case fatality (>5%) and/or permanent health effects 4.16 Likelihood of occurence None Prov en impossibility of transmission to humans through live animals, animal products, vectors or food Extremely rare Probability lower than 1/1000000 Occasional Occurs at an incidence lower than 1/10000 Regular Occurs at an incidence lower than 1/1000 Frequent Occ urs at an incidence higher than 1/1000 4.16 Impact of occurrence on food safety No Not spread in food Negligible Very low level of contamination of food but unlikely to cause problems Low Low level of contamination and can cause disease/infection if organisms ingested in large numbers Medium Probability of spread via food but large numbers of organisms needed to cause problems. Precautions required High High probability of spread via food, small infective dose and strict precautions required 4.16
  • 4. Transmissibility (spread from animal to human) No No transmission possible Negligible No known transmission to humans or no information Low Possible transmission and existing contacts with live animals Medium Possible transmission or contamination through direct or indirect contact or vector/food High Very low species barrier, possible airborne or through the environment 4.16 Spread in humans No Non- transmissible Negligible No known transmission between humans or no information Low Transmission between humans is uncommon Moderate Transmission between humans requires prolonged or high level challenge Rapid Trans mission between humans occurs frequently and is common 4.16 Bioterrorism potential None Agent unavailable or impossible to handle or no harm Negligible Agent available but difficult to handle or low potential harm Low Agent available and easy to handle by pros and labs but low potential harm Medium Agent available and easy to handle by pros and labs and high potential harm Severe Agent available and easy to handle by individuals and high potential harm 4.16 IMPACT ON WIDER SOCIETY - 3 criteria 0 1 2 3 4 Economic direct impact (including cumulative costs (e.g. Enzoonotic vs Epizootic)) None No loss, no control measures Negligible Minor reduction in production Low Production reduced but not banned. Treatment and vaccination Medium Production reduced and partially banned. Test and slaughter High Production reduced and banned. Total slaughter 8.33 Economic indirect impact (social, market) None Products continue to be distributed Negligible Minor impact on distribution of products Low Herd products redirected to lower value markets Medium Market price reduced temporarily by less than 30% High Reduction by more than 30% over a month or a country wide ban 8.33
  • 5. Agriterrorism potential None Agent unavailable or impossible to handle or no spread Negligible Agent available but difficult to handle or low spread or low economic damages Low Agent available and easy to handle by professionals and labs but low spread or low economic damages Medium Agent available and easy to handle by professionals and labs and rapidly spread or high economic damages Severe Agent available and easy to handle by individuals and rapidly spread and great economic damages 8.33 IMPACT ON TRADE - 4 criteria 0 1 2 3 4 Impact on international trade due to existing regulations None No restriction or only at animal level Minor Only at herd level Moderate At zone level and/or a list of commodities, no loss of official status Significant Zone standstill, loss of official status, short recovery period Serious Possible nationwide ban standstill with or without list, official atatus difficult to recover 6.25 Impact on Economic trade due to existing regulations None No restriction or only at animal level Minor Only at herd level Moderate At zone level and/or list of commodities Significant At zone level and/or no list of commodities Serious Nationwide ban/standstill with or without list 6.25 Potential for zoning High Zoning possible at farm level Moderate Zoning possible 1 to 10 kms Low Zoning possible but more than 10 kms Very low Zoning using wider administrative boundaries None Only compartments 6.25 Impact on security of food supply Extremely limited, anecdotal Low value Only in some remote areas Moderate Someremote areas may be temporarily out of stock High Some areas of the country may be out of stock Very High May cause or increase hunger problems 6.25 CONTROL TOOLS - 3 criteria 2 1 0 -1 -2
  • 6. Appropriate diagnostics Need: Yes Availability: No Market Potential: Low Need: Yes Availability: No Market Potential: Yes Need: Yes Availability: Yes (not fully effective) Market Potential: Low to Medium Need: Yes Availability: Yes (not fully effective) Market Potential: Yes Either Need: No or Need: Yes Availability: Yes (fully effective) Market Potential: Yes 16.6 6 Appropriate vaccines Need: Yes Availability: No Market Potential: Low Need: Yes Availability: No Market Potential: Yes Need: Yes Availability: Yes (not fully effective) Market Potential: Low to Medium Need: Yes Availability: Yes (not fully effective) Market Potential: Yes Either Need: No or Need: Yes Availability: Yes (fully effective) Market Potential: Yes 16.6 6 Appropriate pharmaceuticals Need: Yes Availability: No Market Potential: Low Need: Yes Availability: No Market Potential: Yes Need: Bacteria - Yes Need: Virus - Desirable Availability: Bacteria - Yes (not fully effective) Availability: Virus - No Market Potential: Low to Medium Need: Yes Availability: Yes (not fully effective) Market Potential: Yes Either Need: No or Need: Yes Availability: Yes (fully effective) Market Potential: Yes 16.6 6 TOTAL
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